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Lifestyle and Adverse Performance Effects (OGHFA BN)

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Article Information
Category: Human Factors Human Factors
Content source: Flight Safety Foundation Flight Safety Foundation
Content control: EUROCONTROL EUROCONTROL
Operator's Guide to Human Factors in Aviation
Human Performance and Limitations
Lifestyle and Adverse Performance Effects


Briefing Note


Background

Flying is a complex task that requires the full cognitive, judgemental and psychomotor capabilities of a pilot. If these abilities are impaired to any extent, safety can be compromised. Many conditions and substances can cause impairment. For example, all humans occasionally have mild illnesses such as colds that can potentially impair their performance. Some people have chronic conditions such as high blood pressure or elevated cholesterol that are not disabling but require the use of medication to control symptoms. Drugs, both prescription and over-the-counter, can relieve symptoms and, perhaps, even cure the illness. Many people routinely drink alcoholic and/or caffeinated beverages. Each of these uses of drugs, as well as other lifestyle activities, can affect flying, particularly on long-range, monotonous flights, impair the pilot’s abilities and compromise safety.

Introduction

This Briefing Note (BN) covers important lifestyle aspects for pilots—illness, the use of medications and drugs, nutrition and eating habits, alcohol and caffeine intake, and exercise. It is information that you can use to assess your own fitness for flight and to know when to seek the advice of your doctor or flight surgeon. Your personal doctor knows your medical condition best and what is most important for your overall health. He or she, however, may not be trained to appreciate the effects of your medical condition or the drugs he/she prescribes on flight risk. Your flight surgeon, on the other hand, may not be familiar with your overall health but is well aware of the consequences of lifestyle decisions on flight safety. You should make sure that both medical professionals have the information they need about you and your lifestyle to advise you properly and to work as a team.

Determining Fitness to Fly

Your doctor and flight surgeon do not see you daily. They depend on you to seek them out when you think you have a health condition. On a day-to-day basis, however, you have to determine if you are fit to fly or should seek medical attention. If you think of the following question and answer, it will help you make a good decision.


Am I fit to fly?” Yes, I‘M SAFE!


I Illness Am I ill? Do I feel sick in any way?
M Medication I take drugs: will they impair my thinking, judgment or performance?
S Stress Am I mentally fit? Can I devote my full attention to flying?
A Alcohol When did I take the last drink? Am I suffering hangover effects?
F Fatigue Am I physically fatigued? Am I too tired to give 100%?
E Eating Am I hungry? Did I eat too much? Do I have indigestion?


This simple mnemonic, I’M SAFE, is a checklist to help you remember the main lifestyle risk factors that might impair your performance during flight.

Data

There are few statistics on the effect of lifestyle on flight safety, but it is universally acknowledged that an impaired pilot is a safety risk. As mentioned earlier, one has to be fit for flying because it is a demanding task.

An example from military flight illustrates the deleterious effect of illness, drugs and fatigue on flight safety. An F-14 Tomcat crashed on the deck of a U.S. aircraft carrier at night killing several of the ship’s deck crew. The pilot had contracted a severe flu and had taken nasal decongestant drops without telling his flight surgeon. These drops have serious negative side effects on performance, particularly visual performance at night.

The Effect Of Drugs On Flight Safety

A drug can be defined as any chemical substance that has an effect on living tissue but is not used for food. Drugs are used on or administered to humans as:

  • An aid in the diagnosis, treatment or prevention of disease or other abnormal conditions
  • For the relief of pain or suffering
  • To control or improve any physiological or pathological condition.

Drugs can generally be classified into two broad categories—licit and illicit. Licit drugs are often referred to as medications, and illicit drugs are sometimes called “recreational” drugs. This distinction can be blurred when drugs that are legal if prescribed by a doctor are used without medical need or authorization.

Alcohol and caffeine are the most widely used drugs. It is legal to consume alcohol in most locales, but the effects of the misuse of alcohol on transportation safety can be enormous. Many everyday beverages and food products such as coffee, cola and chocolate, contain significant amounts of caffeine.

Medicines

All pilots should know that all medications, even those seeming to be “light,” contain active components with desirable therapeutic benefits but also unwanted and often unpredictable side effects. Such side effects can vary widely across individuals depending on personal sensitivities and the pharmacokinetics of the drug. A drug that can relieve symptoms or cure a condition in one pilot may cause a violent and life-threatening allergic reaction in another.

Flight can also alter the effects of medications. For example, the metabolism of a drug may be altered by flight-induced conditions including mild hypoxia, dehydration and jetlag. The undesirable effects of a drug are also sometimes delayed until well after the drug is taken. Care must especially be exercised when a drug is new on the market or taken in combination with other medications because little may be known about the resulting effect on flight safety.

The following table identifies families of widely-used medicinal drugs, both prescription and over-the-counter (OTC), that are known to have negative effects on alertness, sensory performance, judgement, cognitive and/or psychomotor abilities. As such, these drugs, even when prescribed by your personal doctor, may not be compatible with safe flight unless approved by a flight surgeon.

Note: This table is not meant as a list of drugs for self treatment. It is also not intended to be a comprehensive list of all drugs that can affect flight safety. It is provided to give examples of commonly used medicines that, although beneficial in preventing or curing illness and injury, can be detrimental to the safe performance of a pilot’s duties.
Drug Family Illnesses and Symptoms Treated Potential Negative Effects on Flight Safety
Hypnotics

Drugs that induce sleep, sometimes called soporifics. In general, hypnotics are central nervous system depressants. Barbiturates and benzodiazepines are frequently prescribed hypnotics. Smaller doses of these same drugs may be used as sedatives. Alcohol is included in this drug family.

Insomnia, anxiety Poor sleep quality

Daytime sleepiness

Fatigue

Risk of dependence

Anti-allergy and decongestive drugs

These drugs include antihistamines and nasal decongestant pills and sprays. Many are sold OTC.

Nose and ear infections

Skin or oronasal allergy

Sleepines

Vision trouble

Postural trouble

Vertigo

Anti-flu “cocktails”

These are often combinations of antihistamines, decongestants, cough suppressant and pain relief medications sold OTC and widely advertised.

Colds

Influenza

Mild nose, ear or throat infections

Sleepiness

Fatigue

Vertigo

Vision trouble

Digestive trouble

Bowel irritations

Dry mouth

Anti-coughing (antitussive) drugs

As prescription drugs, these can contain codeine and some antihistamines. OTC versions without codeine are also available

Cough Sleepiness

Fatigue

Digestive trouble

Muscle relaxant drugs

Muscle relaxants help relax muscles, ease pain, and reduce stiffness.

Injury (e.g., sport trauma), back pain, neck tension, muscle tension Sleepiness

"Drunk" feeling

Fatigue

Analgesics (anti-pain drugs)

An analgesic (colloquially known as a “painkiller”) is any member of a diverse group of prescription and OTC drugs used to relieve pain. They include paracetamol (acetaminophen), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates (aspirin), narcotic drugs such as morphine, synthetic drugs with narcotic properties such as tramadol, and various others.

Pain Sleepiness

Digestive trouble

Risk of dependence

Anti-inflammatory drugs

There are a variety of anti-inflammatory drugs including the NSAIDs (discussed above), anabolic steroids and corticosteroids (e.g., prednisone). Anabolic steroids have been used by athletes to build body mass and improve performance.

Oronasal infections, persistent coughs, asthma, tendonitis, vertebral pain Vertigo

Sleepiness (occasionally)

Hyperactivity

Severe withdrawal reactions

Anti-headache drugs

Some relatively new prescription drugs are available to treat or prevent migraine headaches. These include Topiramate (brand name Topamax) and Fiorinal, a combination analgesic medication consisting of aspirin, the barbiturate butalbital and caffeine.

Occasional severe headache

Frequent migraine

Cognitive deficiency (particularly word-finding difficulty)

Sleepiness

Lethargy

Impairment of fine motor skills

Vision abnormality and transient or permanent vision loss

Fatigue

Dizziness

Insomnia

Anxiety

Depression

Digestive trouble

Dependency

Antihypertensive drugs

A class of drugs that are used to treat hypertension (high blood pressure). There are many classes of antihypertensives, which—by varying means—lower blood pressure to reduce the risk of stroke, coronary heart disease and the likelihood of dementia, heart failure and mortality from cardiovascular disease.

High arterial blood pressure Effects vary by drug class but include:

Fatigue

Sleepiness

Decreased tolerance to accelerations

Headache

Dizziness

Confusion

Dry mouth

Fainting, seizure or convulsions (rare)

Anti-diarrhea drugs

OTC medicines such as Immodium® and prescription drugs such as Lomotil®, which act to stop diarrhea and thereby reduce the chance of dehydration.

Diarrhea Fatigue

Sleepiness

Vertigo

Stomach ulcer/GERD drugs

Many OTC and prescription drugs are directed at reducing stomach acid to help cure heartburn caused by ulcers or Gastroesophageal Reflux Disease (GERD).

Ulcer, GERD Headaches (occasionally)

Vertigo

Anti-nausea drugs

There are numerous drugs both OTC (e.g., Dramamine®, Bonine ®) and prescription (e.g., Antivert®) that reduce nausea from motion sickness or illnesses such as middle ear infections. Pilot trainees may be particularly interested in these drugs if they develop symptoms as they adapt to flight conditions.

Motion sickness and middle ear disorders Decreased visual acuity

Decreased glare resistance

Blurred vision

Sleepiness

Headache

Dry mouth

Anti-malaria drugs

Antimalarial drugs are designed to prevent or cure malaria. Some antimalarial agents, particularly chloroquine and hydroxychloroquine, are also used in the treatment of rheumatoid arthritis and lupus associated arthritis. There are many prescription anti-malaria drugs currently on the market.

Prevention or treatment of malaria Psychiatric disorders

Convulsions

Visual problems

Fatigue

Vertigo

Nausea

Diarrhea

Melatonin

Melatonin is a hormone found in all living creatures from algae to humans. Melatonin can be found in the general health supplement market.

Jet lag

(While widely promoted as a “cure” for jet lag, a definitive medical study of this use and its safety has yet to be completed)

Sleepiness

Inflammation in people with nocturnal asthma

Loss of balance

Anti-anxiety drugs

The anti-anxiety or anxiolytic drugs include the benzodiazepines, which are prescribed for short-term relief of severe and disabling anxiety. Common benzodiazepines include lorazepam (Ativan®), clonazepam (Klonopin®), alprazolam (Xanax®), and diazepam (Valium®). Non-benzodiazepines and barbiturates are also in this group.

Anxiety, stress Sleepiness

Fatigue

Impaired memory

Cognitive difficulties

Impaired judgement

Disorientation and vertigo

Loss of coordination

Anti-depression drugs

An antidepressant, is a psychiatric medication or other substance (nutrient or herb) used for alleviating mild or severe depression. These medications are now among the drugs most commonly prescribed by psychiatrists and general practitioners, and their effectiveness and adverse effects are the subject of many studies and competing claims. Depression by itself and the unwanted effects of these drugs are incompatible with safe flight.

Depression

Smoking cessation

Sleepiness

Fatigue

Headaches, tremor

Impaired memory

Cognitive difficulty

Nausea

Diarrhea

Antibiotics

An antibiotic is a chemical compound that inhibits or abolishes the growth of microorganisms, such as bacteria, fungi or protozoans.

Bacterial infections Sometimes vertigo and “drunk” feeling

Fever

Nausea

Allergic reaction

Diarrhea

The information in the table above is just a summary to indicate the wide range of medications used today and their possible adverse effects. It must also be remembered that taking medications in combination or with alcohol can change both the nature and intensity of the deleterious effects.

Remember that all medications are potentially dangerous and that you should not fly after intake of a drug unless the flight surgeon has prescribed it or checked its efficacy and tolerability.

Illicit drugs

Many drugs, although illegal to consume or possess, are nevertheless widely used. Other drugs that have legitimate medical uses can be abused if not taken as prescribed by a doctor or taken for non-medical purposes. People seek a “high” or escape from reality by abusing substances such as:

  • Cannabis (marijuana) - not illegal everywhere
  • Psilocybin mushrooms
  • Opium
  • Heroin - illegal in most countries
  • Cocaine
  • Morphine
  • Methamphetamine (meth).

Almost all illicit drug use leads to some level of impairment that is detrimental to safe flight. Illicit drug use is not only dangerous but also can ruin a flying career. As a pilot, you should never use illicit drugs.

Alcohol

Contrary to popular belief, alcohol acts as a depressant not a stimulant. What is often mistaken for mood elevation from alcohol (e.g., loud speech, aggressive behaviour) is actually a result of its disinhibiting effects. As one drinks, alcohol first affects judgement and removes inhibitions and then degrades psychomotor performance.

Blood alcohol concentration (BAC) is the measure typically used to indicate a person’s degree of impairment. BAC is the weight of alcohol in grams per 100 ml of blood. The time for a person to reach a peak BAC after consuming alcohol varies depending on the rate of absorption of the alcohol into the bloodstream. This absorption rate can be influenced by body build and size, age, gender (females tend to be affected more than males), whether food has been taken with the alcohol and the type of drink.

On average, alcohol is eliminated from the body at the rate of about one standard drink (a BAC of about 0.03) per hour. However, the elimination rate of alcohol can vary greatly by individual depending on factors such as gender, body mass and drinking frequency.

Various BAC levels have been used to define when someone has consumed too much alcohol and therefore is unfit for some activity. For example, a BAC of 0.08 (0.08 grams of alcohol per 100 ml of blood) is used in all 50 of the United States to define a level of intoxication at which it is illegal to drive a car. Many other countries define even lower BAC limits for drivers.

Most countries and airlines have a bottle to throttle rule specifying how much time must elapse from the last drink until a pilot flies. The typical value is 8 hours, although some rules specify 10 or 12 hours. There are also BAC limits for flying, which typically are zero (0.00) or 0.02. An important point for a pilot to note is that alcohol can be impairing even after your BAC returns to zero. Anyone who has ever experienced a hangover can tell you that. Thus, while a nice cocktail and glass of wine at dinner before a noon departure the next day is probably fine, more extensive drinking can significantly increase safety risk even if your BAC is zero when you get to the cockpit.

All of the available scientific evidence shows conclusively that any alcohol use causes impairment with the nature of the effects being dose dependant. At BACs below 0.03, euphoria and some impairment of judgement are evident. As BAC increases above 0.03, functions such as divided attention, choice reaction time, visual perception, tracking and steering, eye movement control, standing steadiness, emergency responses, coordination and information processing judgment have been shown to be significantly impaired. Above a BAC of about 0.05, lack of coordination and problems with gross motor control occur. Although sleep is promoted by alcohol because of its sedative effect, it can also actually impair sleep quality and even cause insomnia.

Alcohol, when consumed in excess amounts, has a wide range of short- and long-term ill effects on an individual's health. Alcohol causes inflammation of the stomach, pancreas, and intestines, which impairs the digestion of food and absorption into blood. Moreover, acetaldehyde (the oxidation product of alcohol) can interfere with the activation of vitamins. Alcohol has a high caloric value; hence it can lead to weight gain when consumed in large quantities. It also causes low blood-sugar levels and dehydration, leading to an increase in appetite.

Caffeine

Caffeine is a stimulant that is contained in many beverages, foods and OTC drugs. The use of caffeine can prevent falling asleep, but it does not necessarily improve performance. The performance of a person who is not significantly fatigued but may be bored or otherwise drowsy from lack of stimulation, can possibly benefit from the stimulant effects of caffeine. On the other hand, a grossly fatigued individual may be kept awake by large dose of caffeine but will still exhibit impaired performance.

Pilots can effectively use caffeine from coffee or tea on long-range flights if they time its intake appropriately. Advice on when to schedule caffeine intake can be found in the Briefing Note How to Cope With Jet Lag in Eastward and Westward Rotations. It must be remembered, however, that caffeine is a drug with possible negative side effects such as insomnia. Also, there have been reported cases of people taking toxic doses of caffeine in an effort to stay awake.

Some myths about drug use

OTC drugs are not dangerous.

Wrong! Any drug, even a vitamin or herb, can be dangerous and can interfere with safe flying. Many of the drugs in the table above can be purchased without a prescription.

If I take a medication well before the time of flight, it will not impair my ability.

Wrong! While some drugs only produce effects for a few hours, many have long-lasting effects. Do not assume the deleterious effects are gone just because your last dose was hours before the flight. Ask your flight surgeon how long you should wait before flying after taking a prescription or OTC drug.

I can take a medication that has been prescribed to another member of my family or a friend suffering from the same symptoms.

Wrong! The same symptoms can be related to different conditions, and each person may react to a given drug differently.

The first few doses of the medicine I was prescribed did not cure my problem. I think I should double the dose or add another medicine.

Wrong! There is an optimal dose for all medicines. Increasing the dose without a flight surgeon’s permission can be dangerous to your health and might impair your piloting abilities. Combinations of drugs can produce unpredictable reactions. Always check with your flight surgeon before mixing medicines.

A little use of illicit drugs is not dangerous as long as I do it well before flight.

Illicit drugs are dangerous to your health and your career. First, you never really know what is contained in drugs purchased illegally. You could be getting anything—even a dangerous poison. Second, the traces of some drugs such as marijuana, can remain in your system for days or even weeks and will be detected by drug tests.

Nutrition and Eating Habits

Fatigue results in part from a decrease in the stock of carbohydrates (glucose) in the body. There are few studies about the specific relationship between nutrition status and the physical performance level of a pilot during a long-haul flight. Nevertheless, it is reasonable to conclude that eating habits and their impact on nutrition can be related to pilot performance and safety.

The energy expenditure of a pilot during a long-haul flight can be estimated at 200 kilocalories per hour (kcal/h). Since the stock of carbohydrates in a typical human provides a storehouse of about 2,500 kcal, the desired glucose blood concentration (glycemia) can be maintained for approximately 8-10 hours between two meals for a man strictly at rest. However, even light physical or mental effort increases the body’s need for glucose. Thus, even for a nominal workload of 150 kcal/h the stored glycemia begins to be used up in four to five hours without eating, resulting in decreased cognitive performance and fatigue.

Based on this simple example, it is reasonable to conclude that food intake is necessary after three or four hours of flight.

In addition to maintaining a sufficient stock of glucose, mental performance must also be maintained by an appropriate nutritional approach and timing. For a normally alert and rested person, the intake of fast (sweets) or slow (potatoes, cereal) release carbohydrates leads to a decreased level of alertness 30 to 60 minutes after intake. Thus, taking carbohydrates, while favorable to physical performance, can lead to a decreased level of cognitive performance. By contrast, a meal rich in proteins (meat, fish, eggs, milk derivatives) seems to improve the cognitive performance of those who are fatigued.

These considerations of nutritional physiology lead to the following principles to follow when flying long-haul flights:

  • The crew should begin a long-haul flight with a high stockpile of energy from a meal consumed sufficiently long before the flight that it will not induce any drowsiness. The optimal intake is about 800 kcal one hour before the flight that includes 50% slow release carbohydrates, 30% fats and 20% proteins
  • If the flight will last more than three hours, food intake should be scheduled during the flight. The energy bars often taken by athletes are not an appropriate substitute for more balanced food intake because they are too rich in carbohydrates.
  • It is also important to drink water during the flight to avoid any decrease in performance and vigilance due to dehydration.
  • After the flight, it is important to eat a meal to recover a good level of performance and alertness.

Some typical menus that will help you follow these principles are shown below.

Before a Flight During a Flight After a Flight
Dinner the day before the flight: "spaghetti party" with 100-150 g of pasta (or potatoes) with white meat (chicken, veal or fish). A cream-based dessert.

Just before the flight (at any time of the day or the night): easily digestible foods rich in calories such as eggs, cheese, white meat, buttered bread, cereals and milk. Drink 250-300 ml of water. Avoid fresh fruits, pastries, cream-based desserts.

Flights over two hours: eat a light snack

Flights up to four hours: 2 cereal-based energy bars can be eaten. Avoid the “high-energy” sports bars. Rehydration with water is not necessary if sufficient water was drunk before the flight.

Flights over four hours: Small snacks should be eaten every two hours after the initial two hours of flight. Consume at least 250 ml of water every four hours.

Eat a small snack (600-800 kcal) followed later by a “real” meal

Physical Exercise

Regular physical exercise improves tolerance to environmental stressors in aeronautics and decreases the duration of post-flight recovery. Three one-hour sessions per week or 15-minute daily workouts are recommended. To improve general physical fitness, all types of endurance activities (e.g., cycling, swimming, jogging, tennis) are recommended. To improve piloting performance (and to avoid any back or neck pain), physical training should focus on the postural muscles (cervical, back, abdominal and thigh muscles).

Just prior to a flight (about 10 minutes) you should “wake up” your muscles in order to avoid any muscular tension while on board. Muscular stretching during the flight is also beneficial. Following a flight, stretching exercises can be very beneficial. However, it is best to wait two hours after landing before engaging in endurance types of exercise for relaxation or fitness.

If your flight is scheduled in the morning, engage in endurance exercise at the end of the day. The reverse is not true, however, if you are scheduled for an afternoon flight. When flying afternoons, you should refrain from strenuous exercise that morning.

Summary of Key Points

  • Safe piloting requires a fully capable individual. No level of impairment is acceptable.
  • Almost all drugs, whether OTC or prescribed, can impair one or more aspects of flying skills.
  • Your personal doctor knows your overall health but may not be familiar with the demands of flight. Always crosscheck any prescribed medicines with your flight surgeon.
  • Alcohol is a drug that can be dangerous to flight even after it is out of your system.
  • Caffeine can be useful if its intake is properly managed.
  • Illicit drug use is not compatible with safe flight, your health or your career goals.
  • Good nutrition can improve your alertness and performance. Eat right and at the correct times.
  • Exercise, if properly timed, promotes better piloting performance and good health.
  • Do not fall prey to popular myths about drug use.
  • Before flying, assess your fitness by remembering to go through the I’m Safe checklist (Illness, Medication, Stress. Alcohol, Fatigue, Eating).

References

Other OGHFA materials

The following OGHFA material complements the above issues:

Briefing Notes:

Checklists:

Situational Example:

Documents and websites

  • DANGUIR (J.) & NICOLAIDIS (S.).- Dependence of sleep on nutriment’s availability.- Physiological Behavior, vol. 22, 1979, pp. 735-740.
  • IRELAND (R.R.).- Pharmacological considerations for serotonin reuptake inhibitor use by aviators.- Aviation, Space, and Environmental Medicine, vol. 73, 2002, pp. 421-429.
  • NEWMAN (D.G.) - Alcohol and Human Performance from an Aviation Perspective: A Review.
  • RTO TECHNICAL REPORT TR 014.- Medication for military aircrew : current use, issues and strategies for expanded options.
  • SCHWEITZER (P.K.).- Drugs that disturb sleep and wakefulness.- In: Principles and practice of sleep medicine. Third edition, KRYGER (M.H.) ; ROTH (T.) ; DEMENT (W.), SAUNDERS (W.B.) publisher, 2000.
  • SMITH (A.P.) & KENDRICK (A.M.).- Meal and performance. In: Handbook of Human Performance. Saiths and Jones (Eds), Academic Press London Publisher, 1992, pp. 1-23.
  • Drug Use Trends in Aviation: Assessing the Risk of Pilot Impairment, NTSB study on which examines trends in the prevalence of over-the-counter, prescription, and illicit drugs identified by toxicology testing of fatally injured pilots between 1990 and 2012. Published in Sept. 2014.



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